| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1986 | New York Yankees | 7 | 8 | 27 | 131.2 | 4.10 | 1.34 | 76 | 50 | 13 | 5.19 | 3.42 |
| 1987 |
| Pittsburgh Pirates |
| 11 |
| 12 |
| 29 |
| 176.1 |
| 3.88 |
| 1.20 |
| 120 |
| 46 |
| 22 |
| 6.12 |
| 2.35 |
| 1988 | Pittsburgh Pirates | 15 | 7 | 33 | 219.1 | 3.08 | 1.11 | 127 | 50 | 21 | 5.21 | 2.05 |
| 1989 | Pittsburgh Pirates | 14 | 12 | 35 | 244.1 | 2.80 | 1.16 | 123 | 69 | 21 | 4.53 | 2.54 |
| 1990 | Pittsburgh Pirates | 22 | 6 | 33 | 231.1 | 2.76 | 1.06 | 131 | 56 | 15 | 5.10 | 2.18 |
| 1991 | Pittsburgh Pirates | 15 | 14 | 35 | 234.2 | 3.07 | 1.31 | 142 | 62 | 16 | 5.45 | 2.38 |
| 1992 | Pittsburgh Pirates | 15 | 11 | 34 | 256.2 | 2.77 | 1.06 | 177 | 54 | 17 | 6.21 | 1.89 |
| 1993 | Houston Astros | 9 | 18 | 34 | 237.2 | 3.79 | 1.27 | 157 | 60 | 18 | 5.95 | 2.27 |
| 1994 | Houston Astros | 12 | 6 | 23 | 164.2 | 2.84 | 1.07 | 121 | 45 | 14 | 6.61 | 2.46 |
| 1995 | Houston Astros | 10 | 9 | 31 | 185.0 | 4.77 | 1.40 | 143 | 54 | 18 | 6.96 | 2.63 |
| 1996 | Houston Astros | 7 | 9 | 30 | 175.1 | 4.57 | 1.53 | 137 | 60 | 21 | 7.03 | 3.08 |
| 1997 | Chicago White Sox | 12 | 11 | 31 | 169.1 | 5.74 | 1.41 | 85 | 69 | 30 | 4.52 | 3.67 |
| 1998 | Baltimore Orioles | 6 | 11 | 23 | 108.2 | 7.29 | 1.54 | 55 | 29 | 20 | 4.56 | 2.40 |
| Career | — | 155 | 134 | 398 | 2535.0 | 3.73 | 1.24 | 1,594 | 704 | 246 | 5.66 | 2.50 |