| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1991 | Montreal Expos | 2 | 5 | 51 | 55.1 | 2.44 | 1.01 | 42 | 17 | 1 | 6.83 | 2.77 |
| 1992 |
| Montreal Expos |
| 8 |
| 7 |
| 70 |
| 85.2 |
| 2.84 |
| 1.34 |
| 63 |
| 34 |
| 1 |
| 6.62 |
| 3.57 |
| 1993 | Montreal Expos | 12 | 5 | 56 | 149.2 | 2.29 | 1.16 | 140 | 54 | 7 | 8.42 | 3.25 |
| 1994 | Montreal Expos | 8 | 6 | 21 | 138.2 | 2.99 | 1.15 | 119 | 40 | 13 | 7.72 | 2.60 |
| 1995 | Montreal Expos | 13 | 14 | 30 | 189.0 | 4.33 | 1.49 | 164 | 74 | 15 | 7.81 | 3.52 |
| 1996 | Montreal Expos | 15 | 11 | 34 | 231.2 | 3.30 | 1.17 | 222 | 55 | 20 | 8.62 | 2.14 |
| 1997 | Seattle Mariners | 16 | 9 | 35 | 234.1 | 3.61 | 1.32 | 189 | 84 | 21 | 7.26 | 3.23 |
| 1998 | Seattle Mariners | 13 | 12 | 32 | 224.2 | 3.97 | 1.29 | 176 | 66 | 33 | 7.05 | 2.64 |
| 1999 | Seattle Mariners | 4 | 14 | 30 | 139.0 | 7.38 | 1.88 | 101 | 73 | 34 | 6.54 | 4.73 |
| 1999 | Texas Rangers | 1 | 0 | 7 | 17.1 | 5.71 | 1.73 | 13 | 10 | 1 | 6.75 | 5.19 |
| 1999 | 5 | 14 | 37 | 156.1 | 7.20 | 1.86 | 114 | 83 | 35 | 6.56 | 4.78 |
| 2000 | Boston Red Sox | 8 | 8 | 38 | 130.0 | 4.78 | 1.56 | 97 | 50 | 16 | 6.72 | 3.46 |
| 2001 | Chicago Cubs | 4 | 4 | 82 | 73.2 | 3.42 | 1.21 | 79 | 23 | 6 | 9.65 | 2.81 |
| 2002 | Chicago Cubs | 5 | 6 | 57 | 51.0 | 6.18 | 1.71 | 44 | 22 | 5 | 7.76 | 3.88 |
| 2002 | St. Louis Cardinals | 3 | 0 | 16 | 18.0 | 3.00 | 1.17 | 12 | 5 | 4 | 6.00 | 2.50 |
| 2002 | 8 | 6 | 73 | 69.0 | 5.35 | 1.57 | 56 | 27 | 9 | 7.30 | 3.52 |
| 2003 | St. Louis Cardinals | 1 | 7 | 62 | 77.2 | 5.68 | 1.64 | 55 | 34 | 17 | 6.37 | 3.94 |
| 2004 | Colorado Rockies | 3 | 8 | 40 | 111.0 | 5.51 | 1.62 | 59 | 44 | 9 | 4.78 | 3.57 |
| 2004 | Arizona Diamondbacks | 0 | 0 | 1 | 1.0 | 0.00 | 0.00 | 1 | 0 | 0 | 9.00 | 0.00 |
| 2004 | 3 | 8 | 41 | 112.0 | 5.46 | 1.61 | 60 | 44 | 9 | 4.82 | 3.54 |
| 2005 | San Francisco Giants | 4 | 7 | 48 | 91.0 | 4.05 | 1.35 | 60 | 31 | 7 | 5.93 | 3.07 |
| 2006 | San Francisco Giants | 1 | 1 | 10 | 15.0 | 7.80 | 2.07 | 7 | 8 | 4 | 4.20 | 4.80 |
| Career | — | 121 | 124 | 720 | 2033.2 | 4.11 | 1.38 | 1,643 | 724 | 214 | 7.27 | 3.20 |