| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1997 | Kansas City Royals | 6 | 9 | 30 | 170.1 | 5.50 | 1.51 | 116 | 52 | 28 | 6.13 | 2.75 |
| 1998 |
| Kansas City Royals |
| 6 |
| 15 |
| 29 |
| 154.2 |
| 5.88 |
| 1.56 |
| 94 |
| 50 |
| 22 |
| 5.47 |
| 2.91 |
| 1999 | Kansas City Royals | 0 | 1 | 3 | 4.0 | 15.75 | 2.50 | 4 | 3 | 1 | 9.00 | 6.75 |
| 1999 | New York Mets | 0 | 0 | 1 | 1.0 | 0.00 | 1.00 | 0 | 0 | 0 | 0.00 | 0.00 |
| 1999 | 0 | 1 | 4 | 5.0 | 12.60 | 2.20 | 4 | 3 | 1 | 7.20 | 5.40 |
| 2000 | New York Mets | 11 | 11 | 31 | 190.2 | 4.01 | 1.26 | 157 | 44 | 18 | 7.41 | 2.08 |
| 2001 | New York Mets | 8 | 12 | 33 | 179.0 | 4.63 | 1.45 | 156 | 43 | 23 | 7.84 | 2.16 |
| 2002 | Milwaukee Brewers | 10 | 16 | 34 | 210.2 | 4.70 | 1.44 | 140 | 76 | 30 | 5.98 | 3.25 |
| 2003 | Milwaukee Brewers | 1 | 12 | 32 | 123.1 | 6.42 | 1.75 | 93 | 45 | 11 | 6.79 | 3.28 |
| 2004 | Chicago Cubs | 6 | 2 | 32 | 129.2 | 3.47 | 1.23 | 90 | 33 | 10 | 6.25 | 2.29 |
| 2005 | Chicago Cubs | 9 | 8 | 46 | 145.1 | 4.52 | 1.57 | 111 | 53 | 14 | 6.87 | 3.28 |
| 2006 | Chicago Cubs | 3 | 8 | 25 | 66.1 | 7.46 | 1.79 | 59 | 33 | 21 | 8.01 | 4.48 |
| 2008 | San Diego Padres | 1 | 2 | 12 | 19.2 | 6.41 | 1.68 | 12 | 11 | 2 | 5.49 | 5.03 |
| 2008 | Colorado Rockies | 4 | 3 | 23 | 64.0 | 4.78 | 1.34 | 43 | 14 | 8 | 6.05 | 1.97 |
| 2008 | 5 | 5 | 35 | 83.2 | 5.16 | 1.42 | 55 | 25 | 10 | 5.92 | 2.69 |
| 2009 | Colorado Rockies | 2 | 0 | 11 | 18.2 | 6.75 | 2.04 | 13 | 3 | 3 | 6.27 | 1.45 |
| Career | — | 67 | 99 | 342 | 1477.1 | 5.04 | 1.48 | 1,088 | 460 | 191 | 6.63 | 2.80 |