| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1998 | St. Louis Cardinals | 45 | 114 | 29 | 1 | 11 | 2 | 5 | 9 | .254 | .292 | .342 |
| .634 |
| 1999 | St. Louis Cardinals | 88 | 220 | 61 | 1 | 19 | 1 | 15 | 24 | .277 | .321 | .359 | .680 |
| 2000 | St. Louis Cardinals | 118 | 323 | 102 | 5 | 39 | 4 | 16 | 26 | .316 | .347 | .418 | .765 |
| 2001 | St. Louis Cardinals | 144 | 564 | 173 | 3 | 38 | 12 | 25 | 43 | .307 | .342 | .383 | .725 |
| 2002 | St. Louis Cardinals | 94 | 342 | 97 | 5 | 27 | 3 | 12 | 27 | .284 | .316 | .389 | .705 |
| 2002 | Philadelphia Phillies | 53 | 206 | 61 | 4 | 22 | 2 | 14 | 14 | .296 | .353 | .427 | .780 |
| 2002 | 147 | 548 | 158 | 9 | 49 | 5 | 26 | 41 | .288 | .330 | .403 | .733 |
| 2003 | Philadelphia Phillies | 122 | 492 | 142 | 14 | 63 | 14 | 42 | 38 | .289 | .352 | .447 | .799 |
| 2004 | Philadelphia Phillies | 126 | 503 | 150 | 17 | 55 | 7 | 27 | 39 | .298 | .345 | .441 | .786 |
| 2005 | Philadelphia Phillies | 43 | 158 | 50 | 3 | 20 | 0 | 12 | 9 | .316 | .376 | .418 | .794 |
| 2005 | Detroit Tigers | 86 | 343 | 116 | 6 | 36 | 4 | 21 | 16 | .338 | .386 | .461 | .847 |
| 2005 | 129 | 501 | 166 | 9 | 56 | 4 | 33 | 25 | .331 | .383 | .447 | .830 |
| 2006 | Detroit Tigers | 110 | 461 | 136 | 4 | 52 | 1 | 17 | 27 | .295 | .329 | .364 | .693 |
| 2007 | Detroit Tigers | 142 | 587 | 200 | 9 | 67 | 7 | 37 | 30 | .341 | .388 | .458 | .846 |
| 2008 | Detroit Tigers | 141 | 580 | 178 | 8 | 58 | 7 | 35 | 43 | .307 | .350 | .417 | .767 |
| 2009 | Detroit Tigers | 153 | 618 | 176 | 10 | 72 | 7 | 36 | 46 | .285 | .331 | .396 | .727 |
| 2010 | Philadelphia Phillies | 132 | 554 | 165 | 6 | 52 | 5 | 32 | 47 | .298 | .339 | .386 | .725 |
| 2011 | Philadelphia Phillies | 122 | 469 | 130 | 5 | 50 | 3 | 42 | 44 | .277 | .335 | .339 | .674 |
| 2012 | Philadelphia Phillies | 90 | 303 | 78 | 2 | 19 | 0 | 18 | 25 | .257 | .302 | .327 | .629 |
| 2013 | Miami Marlins | 118 | 377 | 98 | 1 | 23 | 2 | 23 | 31 | .260 | .315 | .302 | .617 |
| Career | — | 1,927 | 7,214 | 2,142 | 104 | 723 | 81 | 429 | 538 | .297 | .343 | .397 | .740 |