| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1998 | Atlanta Braves | 5 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | .333 | .333 | .333 |
| .666 |
| 1999 | Atlanta Braves | 7 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | .000 | .000 | .000 | .000 |
| 2000 | Atlanta Braves | 22 | 13 | 4 | 0 | 3 | 0 | 2 | 1 | .308 | .400 | .385 | .785 |
| 2001 | Atlanta Braves | 66 | 164 | 47 | 3 | 20 | 2 | 12 | 19 | .287 | .350 | .390 | .740 |
| 2002 | Atlanta Braves | 72 | 212 | 63 | 5 | 23 | 2 | 12 | 24 | .297 | .339 | .429 | .768 |
| 2003 | Atlanta Braves | 103 | 266 | 70 | 6 | 22 | 1 | 16 | 49 | .263 | .316 | .383 | .699 |
| 2004 | Atlanta Braves | 118 | 309 | 74 | 3 | 31 | 1 | 23 | 53 | .239 | .293 | .320 | .613 |
| 2005 | Texas Rangers | 66 | 148 | 36 | 8 | 20 | 1 | 16 | 35 | .243 | .325 | .439 | .764 |
| 2006 | Texas Rangers | 136 | 520 | 154 | 13 | 74 | 4 | 44 | 102 | .296 | .357 | .456 | .813 |
| 2007 | Chicago Cubs | 149 | 502 | 147 | 10 | 72 | 1 | 58 | 93 | .293 | .371 | .420 | .791 |
| 2008 | Chicago Cubs | 149 | 505 | 144 | 21 | 87 | 6 | 69 | 106 | .285 | .376 | .481 | .857 |
| 2009 | Cleveland Indians | 71 | 278 | 75 | 13 | 50 | 1 | 29 | 63 | .270 | .342 | .457 | .799 |
| 2009 | St. Louis Cardinals | 68 | 237 | 54 | 10 | 28 | 2 | 18 | 58 | .228 | .291 | .405 | .696 |
| 2009 | 139 | 515 | 129 | 23 | 78 | 3 | 47 | 121 | .250 | .319 | .433 | .752 |
| 2010 | San Francisco Giants | 26 | 93 | 18 | 1 | 10 | 0 | 9 | 16 | .194 | .279 | .258 | .537 |
| 2011 | San Francisco Giants | 47 | 86 | 24 | 0 | 12 | 1 | 8 | 18 | .279 | .351 | .302 | .653 |
| 2012 | Washington Nationals | 48 | 85 | 16 | 0 | 6 | 1 | 14 | 18 | .188 | .300 | .247 | .547 |
| 2013 | Toronto Blue Jays | 88 | 204 | 48 | 7 | 36 | 0 | 28 | 49 | .235 | .326 | .407 | .733 |
| Career | — | 1,241 | 3,633 | 975 | 100 | 494 | 23 | 358 | 707 | .268 | .340 | .412 | .752 |