| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1999 | Chicago White Sox | 127 | 492 | 144 | 16 | 84 | 4 | 13 | 72 | .293 | .312 | .463 |
| .775 |
| 2000 | Chicago White Sox | 152 | 572 | 172 | 24 | 92 | 13 | 38 | 94 | .301 | .345 | .484 | .829 |
| 2001 | Chicago White Sox | 150 | 558 | 150 | 24 | 84 | 17 | 38 | 85 | .269 | .321 | .468 | .789 |
| 2002 | Chicago White Sox | 140 | 492 | 130 | 26 | 80 | 1 | 75 | 73 | .264 | .359 | .484 | .843 |
| 2003 | Chicago White Sox | 158 | 623 | 181 | 31 | 113 | 18 | 37 | 91 | .291 | .331 | .499 | .830 |
| 2004 | Chicago White Sox | 153 | 591 | 180 | 31 | 99 | 11 | 54 | 86 | .305 | .366 | .525 | .891 |
| 2005 | Milwaukee Brewers | 162 | 618 | 164 | 32 | 114 | 13 | 57 | 87 | .265 | .324 | .487 | .811 |
| 2006 | Milwaukee Brewers | 102 | 388 | 111 | 28 | 81 | 12 | 38 | 39 | .286 | .347 | .549 | .896 |
| 2006 | Texas Rangers | 59 | 236 | 76 | 9 | 35 | 7 | 20 | 26 | .322 | .369 | .525 | .894 |
| 2006 | 161 | 624 | 187 | 37 | 116 | 19 | 58 | 65 | .300 | .355 | .540 | .895 |
| 2007 | Houston Astros | 162 | 627 | 190 | 32 | 119 | 10 | 53 | 63 | .303 | .354 | .528 | .882 |
| 2008 | Houston Astros | 115 | 436 | 137 | 28 | 100 | 4 | 37 | 49 | .314 | .368 | .569 | .937 |
| 2009 | Houston Astros | 160 | 610 | 183 | 26 | 102 | 5 | 41 | 51 | .300 | .343 | .489 | .832 |
| 2010 | Houston Astros | 157 | 605 | 149 | 24 | 89 | 3 | 37 | 59 | .246 | .291 | .417 | .708 |
| 2011 | Houston Astros | 155 | 585 | 161 | 18 | 94 | 4 | 59 | 60 | .275 | .342 | .446 | .788 |
| 2012 | Houston Astros | 66 | 258 | 74 | 5 | 29 | 0 | 19 | 17 | .287 | .336 | .411 | .747 |
| 2012 | Miami Marlins | 81 | 292 | 71 | 4 | 48 | 3 | 39 | 32 | .243 | .328 | .325 | .653 |
| 2012 | 147 | 550 | 145 | 9 | 77 | 3 | 58 | 49 | .264 | .332 | .365 | .697 |
| Career | — | 2,099 | 7,983 | 2,273 | 358 | 1,363 | 125 | 655 | 984 | .285 | .339 | .483 | .822 |
