| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1999 | Oakland Athletics | 40 | 136 | 38 | 3 | 21 | 1 | 18 | 11 | .279 | .363 | .397 |
| .760 |
| 2000 | Oakland Athletics | 143 | 419 | 101 | 14 | 62 | 1 | 38 | 64 | .241 | .311 | .387 | .698 |
| 2001 | Oakland Athletics | 136 | 453 | 115 | 15 | 60 | 1 | 37 | 68 | .254 | .316 | .408 | .724 |
| 2002 | Oakland Athletics | 136 | 403 | 94 | 7 | 42 | 0 | 43 | 64 | .233 | .313 | .335 | .648 |
| 2003 | Oakland Athletics | 140 | 483 | 132 | 21 | 78 | 0 | 33 | 79 | .273 | .331 | .458 | .789 |
| 2004 | San Diego Padres | 111 | 384 | 106 | 18 | 63 | 1 | 35 | 45 | .276 | .341 | .477 | .818 |
| 2005 | San Diego Padres | 99 | 369 | 107 | 12 | 58 | 1 | 18 | 40 | .290 | .322 | .450 | .772 |
| 2006 | Baltimore Orioles | 144 | 501 | 138 | 23 | 91 | 1 | 43 | 79 | .275 | .343 | .479 | .822 |
| 2007 | Baltimore Orioles | 106 | 364 | 94 | 9 | 62 | 1 | 36 | 59 | .258 | .333 | .382 | .715 |
| 2008 | Baltimore Orioles | 133 | 463 | 119 | 15 | 65 | 0 | 32 | 62 | .257 | .308 | .406 | .714 |
| 2009 | Cincinnati Reds | 81 | 287 | 74 | 5 | 37 | 1 | 33 | 34 | .258 | .336 | .362 | .698 |
| 2010 | Cincinnati Reds | 97 | 313 | 93 | 7 | 48 | 0 | 29 | 49 | .297 | .364 | .428 | .792 |
| 2011 | Cincinnati Reds | 91 | 298 | 84 | 12 | 36 | 0 | 23 | 41 | .282 | .341 | .446 | .787 |
| 2012 | Colorado Rockies | 52 | 184 | 40 | 5 | 28 | 0 | 6 | 32 | .217 | .247 | .353 | .600 |
| 2013 | Los Angeles Dodgers | 17 | 48 | 10 | 3 | 6 | 1 | 6 | 7 | .208 | .291 | .438 | .729 |
| Career | — | 1,526 | 5,105 | 1,345 | 169 | 757 | 9 | 430 | 734 | .263 | .327 | .417 | .744 |