| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2001 | Philadelphia Phillies | 4 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | .400 | .400 | .400 |
| .800 |
| 2002 | Philadelphia Phillies | 9 | 6 | 1 | 0 | 0 | 0 | 0 | 3 | .167 | .167 | .167 | .334 |
| 2003 | Philadelphia Phillies | 64 | 92 | 20 | 1 | 4 | 2 | 7 | 22 | .217 | .273 | .272 | .545 |
| 2004 | Minnesota Twins | 38 | 91 | 23 | 2 | 12 | 6 | 12 | 19 | .253 | .340 | .319 | .659 |
| 2005 | Minnesota Twins | 112 | 394 | 94 | 4 | 26 | 13 | 36 | 86 | .239 | .301 | .335 | .636 |
| 2006 | Minnesota Twins | 135 | 459 | 133 | 1 | 45 | 17 | 47 | 68 | .290 | .352 | .373 | .725 |
| 2007 | Minnesota Twins | 150 | 472 | 99 | 1 | 25 | 16 | 55 | 90 | .210 | .291 | .271 | .562 |
| 2008 | Minnesota Twins | 99 | 338 | 96 | 2 | 28 | 15 | 32 | 57 | .284 | .344 | .382 | .726 |
| 2009 | Minnesota Twins | 125 | 359 | 82 | 1 | 38 | 16 | 61 | 70 | .228 | .337 | .284 | .621 |
| 2010 | Minnesota Twins | 88 | 252 | 60 | 1 | 20 | 6 | 28 | 50 | .238 | .313 | .302 | .615 |
| 2011 | St. Louis Cardinals | 63 | 133 | 37 | 1 | 20 | 1 | 25 | 21 | .278 | .388 | .421 | .809 |
| 2012 | Boston Red Sox | 65 | 125 | 25 | 1 | 10 | 5 | 19 | 33 | .200 | .301 | .272 | .573 |
| 2012 | Los Angeles Dodgers | 22 | 35 | 10 | 0 | 0 | 1 | 6 | 9 | .286 | .390 | .314 | .704 |
| 2012 | 87 | 160 | 35 | 1 | 10 | 6 | 25 | 42 | .219 | .321 | .281 | .602 |
| 2013 | Los Angeles Dodgers | 116 | 294 | 75 | 2 | 21 | 3 | 33 | 67 | .255 | .328 | .327 | .655 |
| 2014 | Oakland Athletics | 73 | 198 | 41 | 2 | 14 | 3 | 25 | 56 | .207 | .296 | .293 | .589 |
| Career | — | 1,163 | 3,253 | 798 | 19 | 263 | 104 | 386 | 651 | .245 | .323 | .323 | .646 |