| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2001 | St. Louis Cardinals | 161 | 590 | 194 | 37 | 130 | 1 | 69 | 93 | .329 | .403 | .610 |
| 1.013 |
| 2002 | St. Louis Cardinals | 157 | 590 | 185 | 34 | 127 | 2 | 72 | 69 | .314 | .394 | .561 | .955 |
| 2003 | St. Louis Cardinals | 157 | 591 | 212 | 43 | 124 | 5 | 79 | 65 | .359 | .439 | .667 | 1.106 |
| 2004 | St. Louis Cardinals | 154 | 592 | 196 | 46 | 123 | 5 | 84 | 52 | .331 | .415 | .657 | 1.072 |
| 2005 | St. Louis Cardinals | 161 | 591 | 195 | 41 | 117 | 16 | 97 | 65 | .330 | .430 | .609 | 1.039 |
| 2006 | St. Louis Cardinals | 143 | 535 | 177 | 49 | 137 | 7 | 92 | 50 | .331 | .431 | .671 | 1.102 |
| 2007 | St. Louis Cardinals | 158 | 565 | 185 | 32 | 103 | 2 | 99 | 58 | .327 | .429 | .568 | .997 |
| 2008 | St. Louis Cardinals | 148 | 524 | 187 | 37 | 116 | 7 | 104 | 54 | .357 | .462 | .653 | 1.115 |
| 2009 | St. Louis Cardinals | 160 | 568 | 186 | 47 | 135 | 16 | 115 | 64 | .327 | .443 | .658 | 1.101 |
| 2010 | St. Louis Cardinals | 159 | 587 | 183 | 42 | 118 | 14 | 103 | 76 | .312 | .414 | .596 | 1.010 |
| 2011 | St. Louis Cardinals | 147 | 579 | 173 | 37 | 99 | 9 | 61 | 58 | .299 | .366 | .541 | .907 |
| 2012 | Los Angeles Angels | 154 | 607 | 173 | 30 | 105 | 8 | 52 | 76 | .285 | .343 | .516 | .859 |
| 2013 | Los Angeles Angels | 99 | 391 | 101 | 17 | 64 | 1 | 40 | 55 | .258 | .330 | .437 | .767 |
| 2014 | Los Angeles Angels | 159 | 633 | 172 | 28 | 105 | 5 | 48 | 71 | .272 | .324 | .466 | .790 |
| 2015 | Los Angeles Angels | 157 | 602 | 147 | 40 | 95 | 5 | 50 | 72 | .244 | .307 | .480 | .787 |
| 2016 | Los Angeles Angels | 152 | 593 | 159 | 31 | 119 | 4 | 49 | 75 | .268 | .323 | .457 | .780 |
| 2017 | Los Angeles Angels | 149 | 593 | 143 | 23 | 101 | 3 | 37 | 93 | .241 | .286 | .386 | .672 |
| 2018 | Los Angeles Angels | 117 | 465 | 114 | 19 | 64 | 1 | 28 | 65 | .245 | .289 | .411 | .700 |
| 2019 | Los Angeles Angels | 131 | 491 | 120 | 23 | 93 | 3 | 43 | 68 | .244 | .305 | .430 | .735 |
| 2020 | Los Angeles Angels | 39 | 152 | 34 | 6 | 25 | 0 | 9 | 25 | .224 | .270 | .395 | .665 |
| 2021 | Los Angeles Angels | 24 | 86 | 17 | 5 | 12 | 1 | 3 | 13 | .198 | .250 | .372 | .622 |
| 2021 | Los Angeles Dodgers | 85 | 189 | 48 | 12 | 38 | 1 | 11 | 32 | .254 | .299 | .460 | .759 |
| 2021 | 109 | 275 | 65 | 17 | 50 | 2 | 14 | 45 | .236 | .284 | .433 | .717 |
| 2022 | St. Louis Cardinals | 109 | 307 | 83 | 24 | 68 | 1 | 28 | 55 | .270 | .345 | .550 | .895 |
| Career | — | 3,080 | 11,421 | 3,384 | 703 | 2,218 | 117 | 1,373 | 1,404 | .296 | .374 | .544 | .918 |
