| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2005 | Los Angeles Angels | 1 | 0 | 28 | 34.2 | 3.89 | 1.21 | 30 | 14 | 6 | 7.79 | 3.63 |
| 2006 |
| Kansas City Royals |
| 1 |
| 3 |
| 64 |
| 73.2 |
| 4.40 |
| 1.24 |
| 57 |
| 17 |
| 10 |
| 6.96 |
| 2.08 |
| 2007 | Kansas City Royals | 1 | 3 | 62 | 87.2 | 3.80 | 1.28 | 66 | 19 | 9 | 6.78 | 1.95 |
| 2008 | Kansas City Royals | 1 | 2 | 40 | 52.2 | 5.98 | 1.33 | 38 | 14 | 15 | 6.49 | 2.39 |
| 2009 | Colorado Rockies | 0 | 3 | 27 | 24.2 | 6.20 | 1.58 | 22 | 12 | 3 | 8.03 | 4.38 |
| 2010 | Washington Nationals | 1 | 0 | 39 | 49.0 | 2.02 | 0.80 | 49 | 9 | 5 | 9.00 | 1.65 |
| 2011 | Tampa Bay Rays | 3 | 4 | 71 | 67.2 | 2.93 | 0.92 | 61 | 18 | 7 | 8.11 | 2.39 |
| 2012 | Tampa Bay Rays | 2 | 6 | 76 | 67.0 | 3.63 | 0.99 | 84 | 17 | 9 | 11.28 | 2.28 |
| 2013 | Tampa Bay Rays | 3 | 8 | 80 | 71.1 | 3.41 | 1.14 | 74 | 34 | 7 | 9.34 | 4.29 |
| 2014 | Tampa Bay Rays | 3 | 4 | 69 | 63.1 | 4.41 | 1.18 | 74 | 15 | 9 | 10.52 | 2.13 |
| 2015 | Los Angeles Dodgers | 3 | 1 | 33 | 29.0 | 4.34 | 1.24 | 24 | 8 | 6 | 7.45 | 2.48 |
| 2016 | Seattle Mariners | 1 | 0 | 26 | 23.1 | 5.40 | 1.33 | 28 | 7 | 7 | 10.80 | 2.70 |
| 2016 | Chicago Cubs | 0 | 1 | 5 | 4.0 | 9.00 | 1.75 | 5 | 1 | 2 | 11.25 | 2.25 |
| 2016 | 1 | 1 | 31 | 27.1 | 5.93 | 1.39 | 33 | 8 | 9 | 10.87 | 2.63 |
| Career | — | 20 | 35 | 620 | 648.0 | 4.03 | 1.16 | 612 | 185 | 95 | 8.50 | 2.57 |