| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2003 | Florida Marlins | 87 | 314 | 84 | 12 | 62 | 0 | 25 | 84 | .268 | .325 | .468 |
| .793 |
| 2004 | Florida Marlins | 160 | 603 | 177 | 33 | 112 | 5 | 68 | 148 | .294 | .366 | .512 | .878 |
| 2005 | Florida Marlins | 158 | 613 | 198 | 33 | 116 | 1 | 64 | 125 | .323 | .385 | .561 | .946 |
| 2006 | Florida Marlins | 158 | 576 | 195 | 26 | 114 | 9 | 86 | 108 | .339 | .430 | .568 | .998 |
| 2007 | Florida Marlins | 157 | 588 | 188 | 34 | 119 | 2 | 79 | 127 | .320 | .401 | .565 | .966 |
| 2008 | Detroit Tigers | 160 | 616 | 180 | 37 | 127 | 1 | 56 | 126 | .292 | .349 | .537 | .886 |
| 2009 | Detroit Tigers | 160 | 611 | 198 | 34 | 103 | 6 | 68 | 107 | .324 | .396 | .547 | .943 |
| 2010 | Detroit Tigers | 150 | 548 | 180 | 38 | 126 | 3 | 89 | 95 | .328 | .420 | .622 | 1.042 |
| 2011 | Detroit Tigers | 161 | 572 | 197 | 30 | 105 | 2 | 108 | 89 | .344 | .448 | .586 | 1.034 |
| 2012 | Detroit Tigers | 161 | 622 | 205 | 44 | 139 | 4 | 66 | 98 | .330 | .393 | .606 | .999 |
| 2013 | Detroit Tigers | 148 | 555 | 193 | 44 | 137 | 3 | 90 | 94 | .348 | .442 | .636 | 1.078 |
| 2014 | Detroit Tigers | 159 | 611 | 191 | 25 | 109 | 1 | 60 | 117 | .313 | .371 | .524 | .895 |
| 2015 | Detroit Tigers | 119 | 429 | 145 | 18 | 76 | 1 | 77 | 82 | .338 | .440 | .534 | .974 |
| 2016 | Detroit Tigers | 158 | 595 | 188 | 38 | 108 | 0 | 75 | 116 | .316 | .393 | .563 | .956 |
| 2017 | Detroit Tigers | 130 | 469 | 117 | 16 | 60 | 0 | 54 | 110 | .249 | .329 | .399 | .728 |
| 2018 | Detroit Tigers | 38 | 134 | 40 | 3 | 22 | 0 | 22 | 27 | .299 | .395 | .448 | .843 |
| 2019 | Detroit Tigers | 136 | 493 | 139 | 12 | 59 | 0 | 48 | 108 | .282 | .346 | .398 | .744 |
| 2020 | Detroit Tigers | 57 | 204 | 51 | 10 | 35 | 1 | 24 | 51 | .250 | .329 | .417 | .746 |
| 2021 | Detroit Tigers | 130 | 472 | 121 | 15 | 75 | 0 | 40 | 118 | .256 | .316 | .386 | .702 |
| 2022 | Detroit Tigers | 112 | 397 | 101 | 5 | 43 | 1 | 28 | 101 | .254 | .305 | .317 | .622 |
| 2023 | Detroit Tigers | 98 | 334 | 86 | 4 | 34 | 0 | 31 | 74 | .257 | .322 | .353 | .675 |
| Career | — | 2,797 | 10,356 | 3,174 | 511 | 1,881 | 40 | 1,258 | 2,105 | .306 | .382 | .518 | .900 |
