| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2002 | Los Angeles Dodgers | 8 | 10 | 2 | 1 | 2 | 0 | 2 | 4 | .200 | .385 | .600 |
| .985 |
| 2003 | Los Angeles Dodgers | 40 | 124 | 32 | 10 | 18 | 0 | 13 | 42 | .258 | .336 | .556 | .892 |
| 2004 | Los Angeles Dodgers | 70 | 165 | 28 | 5 | 15 | 0 | 15 | 62 | .170 | .253 | .291 | .544 |
| 2005 | Pittsburgh Pirates | 40 | 108 | 24 | 3 | 15 | 0 | 6 | 24 | .222 | .263 | .380 | .643 |
| 2005 | San Diego Padres | 11 | 17 | 6 | 0 | 0 | 0 | 0 | 4 | .353 | .389 | .471 | .860 |
| 2005 | 51 | 125 | 30 | 3 | 15 | 0 | 6 | 28 | .240 | .279 | .392 | .671 |
| 2006 | Cincinnati Reds | 90 | 247 | 63 | 21 | 52 | 0 | 37 | 75 | .255 | .353 | .579 | .932 |
| 2007 | Cincinnati Reds | 112 | 311 | 63 | 17 | 39 | 0 | 30 | 92 | .203 | .271 | .399 | .670 |
| 2008 | Cincinnati Reds | 52 | 134 | 31 | 3 | 13 | 0 | 32 | 36 | .231 | .381 | .366 | .747 |
| 2008 | Boston Red Sox | 8 | 8 | 1 | 0 | 0 | 0 | 0 | 3 | .125 | .125 | .125 | .250 |
| 2008 | 60 | 142 | 32 | 3 | 13 | 0 | 32 | 39 | .225 | .369 | .352 | .721 |
| 2009 | Atlanta Braves | 54 | 128 | 35 | 7 | 20 | 0 | 21 | 39 | .273 | .380 | .508 | .888 |
| 2010 | Atlanta Braves | 59 | 121 | 35 | 2 | 28 | 0 | 20 | 28 | .289 | .392 | .479 | .871 |
| 2011 | Atlanta Braves | 52 | 152 | 40 | 6 | 23 | 0 | 16 | 51 | .263 | .333 | .428 | .761 |
| 2012 | Atlanta Braves | 62 | 176 | 45 | 9 | 23 | 1 | 18 | 60 | .256 | .321 | .449 | .770 |
| 2013 | Boston Red Sox | 36 | 102 | 22 | 4 | 10 | 1 | 11 | 42 | .216 | .298 | .382 | .680 |
| 2014 | Boston Red Sox | 50 | 152 | 28 | 7 | 15 | 0 | 16 | 58 | .184 | .260 | .368 | .628 |
| 2015 | Chicago Cubs | 72 | 159 | 28 | 1 | 9 | 1 | 20 | 61 | .176 | .267 | .252 | .519 |
| 2016 | Chicago Cubs | 67 | 166 | 38 | 10 | 32 | 0 | 30 | 54 | .229 | .338 | .446 | .784 |
| Career | — | 883 | 2,280 | 521 | 106 | 314 | 3 | 287 | 735 | .229 | .316 | .423 | .739 |