| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2005 | New York Yankees | 132 | 522 | 155 | 14 | 62 | 1 | 16 | 68 | .297 | .320 | .458 | .778 |
| 2006 |
| New York Yankees |
| 122 |
| 482 |
| 165 |
| 15 |
| 78 |
| 5 |
| 18 |
| 54 |
| .342 |
| .365 |
| .525 |
| .890 |
| 2007 | New York Yankees | 160 | 617 | 189 | 19 | 97 | 4 | 39 | 85 | .306 | .353 | .488 | .841 |
| 2008 | New York Yankees | 159 | 597 | 162 | 14 | 72 | 2 | 26 | 65 | .271 | .305 | .410 | .715 |
| 2009 | New York Yankees | 161 | 637 | 204 | 25 | 85 | 5 | 30 | 63 | .320 | .352 | .520 | .872 |
| 2010 | New York Yankees | 160 | 626 | 200 | 29 | 109 | 3 | 57 | 77 | .319 | .381 | .534 | .915 |
| 2011 | New York Yankees | 159 | 623 | 188 | 28 | 118 | 8 | 38 | 96 | .302 | .349 | .533 | .882 |
| 2012 | New York Yankees | 161 | 627 | 196 | 33 | 94 | 3 | 61 | 96 | .313 | .379 | .550 | .929 |
| 2013 | New York Yankees | 160 | 605 | 190 | 27 | 107 | 7 | 65 | 85 | .314 | .383 | .516 | .899 |
| 2014 | Seattle Mariners | 157 | 595 | 187 | 14 | 82 | 10 | 61 | 68 | .314 | .382 | .454 | .836 |
| 2015 | Seattle Mariners | 156 | 624 | 179 | 21 | 79 | 2 | 43 | 107 | .287 | .334 | .446 | .780 |
| 2016 | Seattle Mariners | 161 | 655 | 195 | 39 | 103 | 0 | 47 | 100 | .298 | .350 | .533 | .883 |
| 2017 | Seattle Mariners | 150 | 592 | 166 | 23 | 97 | 1 | 49 | 85 | .280 | .338 | .453 | .791 |
| 2018 | Seattle Mariners | 80 | 310 | 94 | 10 | 50 | 0 | 32 | 47 | .303 | .374 | .471 | .845 |
| 2019 | New York Mets | 107 | 390 | 100 | 13 | 39 | 0 | 25 | 69 | .256 | .307 | .428 | .735 |
| 2020 | New York Mets | 49 | 171 | 54 | 10 | 30 | 0 | 9 | 24 | .316 | .352 | .544 | .896 |
| 2022 | New York Mets | 12 | 41 | 8 | 1 | 3 | 0 | 2 | 11 | .195 | .233 | .268 | .501 |
| 2022 | San Diego Padres | 12 | 33 | 3 | 0 | 1 | 0 | 1 | 10 | .091 | .118 | .091 | .209 |
| 2022 | Atlanta Braves | 9 | 26 | 4 | 0 | 0 | 0 | 1 | 4 | .154 | .185 | .192 | .377 |
| 2022 | 3 teams | 33 | 100 | 15 | 1 | 4 | 0 | 4 | 25 | .150 | .183 | .190 | .373 |
| Career | — | 2,267 | 8,773 | 2,639 | 335 | 1,306 | 51 | 620 | 1,214 | .301 | .351 | .488 | .839 |