| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2004 | Cleveland Indians | 43 | 138 | 34 | 4 | 24 | 2 | 14 | 34 | .246 | .333 | .406 |
| .739 |
| 2005 | Cleveland Indians | 158 | 640 | 185 | 22 | 81 | 22 | 52 | 132 | .289 | .348 | .484 | .832 |
| 2006 | Cleveland Indians | 162 | 655 | 190 | 28 | 76 | 22 | 78 | 153 | .290 | .375 | .533 | .908 |
| 2007 | Cleveland Indians | 162 | 628 | 174 | 24 | 78 | 33 | 101 | 155 | .277 | .390 | .462 | .852 |
| 2008 | Cleveland Indians | 157 | 634 | 170 | 33 | 90 | 38 | 98 | 130 | .268 | .374 | .502 | .876 |
| 2009 | Cleveland Indians | 106 | 436 | 108 | 18 | 64 | 13 | 60 | 92 | .248 | .343 | .445 | .788 |
| 2010 | Cleveland Indians | 33 | 128 | 27 | 0 | 13 | 4 | 9 | 35 | .211 | .271 | .289 | .560 |
| 2011 | Cleveland Indians | 71 | 268 | 60 | 10 | 32 | 0 | 18 | 85 | .224 | .285 | .422 | .707 |
| 2014 | Boston Red Sox | 52 | 185 | 40 | 2 | 15 | 5 | 19 | 41 | .216 | .288 | .324 | .612 |
| 2014 | Philadelphia Phillies | 60 | 162 | 41 | 3 | 12 | 1 | 14 | 35 | .253 | .313 | .389 | .702 |
| 2014 | 112 | 347 | 81 | 5 | 27 | 6 | 33 | 76 | .233 | .299 | .354 | .653 |
| 2015 | Philadelphia Phillies | 39 | 98 | 24 | 0 | 6 | 0 | 6 | 23 | .245 | .288 | .296 | .584 |
| 2015 | Tampa Bay Rays | 58 | 175 | 45 | 6 | 27 | 3 | 14 | 37 | .257 | .318 | .429 | .747 |
| 2015 | 97 | 273 | 69 | 6 | 33 | 3 | 20 | 60 | .253 | .307 | .381 | .688 |
| Career | — | 1,101 | 4,147 | 1,098 | 150 | 518 | 143 | 483 | 952 | .265 | .349 | .457 | .806 |
