| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2006 | Los Angeles Dodgers | 121 | 415 | 117 | 10 | 65 | 10 | 45 | 57 | .282 | .355 | .436 |
| .791 |
| 2007 | Los Angeles Dodgers | 151 | 540 | 158 | 19 | 87 | 21 | 67 | 89 | .293 | .374 | .469 | .843 |
| 2008 | Los Angeles Dodgers | 155 | 553 | 155 | 13 | 69 | 18 | 90 | 83 | .280 | .385 | .396 | .781 |
| 2009 | Los Angeles Dodgers | 143 | 505 | 126 | 7 | 53 | 11 | 69 | 80 | .250 | .352 | .329 | .681 |
| 2010 | Los Angeles Dodgers | 97 | 331 | 82 | 5 | 26 | 6 | 48 | 61 | .248 | .347 | .332 | .679 |
| 2011 | New York Yankees | 125 | 417 | 99 | 18 | 65 | 8 | 50 | 81 | .237 | .324 | .408 | .732 |
| 2012 | New York Yankees | 133 | 422 | 89 | 21 | 53 | 6 | 53 | 95 | .211 | .311 | .403 | .714 |
| 2013 | Pittsburgh Pirates | 127 | 438 | 99 | 15 | 55 | 9 | 58 | 108 | .226 | .327 | .377 | .704 |
| 2014 | Pittsburgh Pirates | 111 | 379 | 110 | 11 | 67 | 4 | 59 | 78 | .290 | .402 | .430 | .832 |
| 2015 | Toronto Blue Jays | 129 | 441 | 106 | 23 | 77 | 4 | 53 | 106 | .240 | .329 | .458 | .787 |
| 2016 | Toronto Blue Jays | 137 | 455 | 105 | 20 | 74 | 2 | 64 | 148 | .231 | .335 | .398 | .733 |
| 2017 | Toronto Blue Jays | 91 | 307 | 68 | 13 | 35 | 1 | 50 | 83 | .221 | .343 | .388 | .731 |
| 2018 | Toronto Blue Jays | 90 | 289 | 56 | 10 | 25 | 0 | 56 | 82 | .194 | .338 | .325 | .663 |
| 2019 | Los Angeles Dodgers | 83 | 209 | 46 | 6 | 20 | 1 | 30 | 60 | .220 | .337 | .330 | .667 |
| Career | — | 1,693 | 5,701 | 1,416 | 191 | 771 | 101 | 792 | 1,211 | .248 | .349 | .397 | .746 |