| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2004 | Toronto Blue Jays | 1 | 0 | 3 | 4.2 | 0.00 | 0.86 | 2 | 1 | 0 | 3.86 | 1.93 |
| 2005 |
| Toronto Blue Jays |
| 1 |
| 0 |
| 20 |
| 35.2 |
| 6.56 |
| 1.74 |
| 17 |
| 20 |
| 8 |
| 4.29 |
| 5.05 |
| 2006 | Toronto Blue Jays | 1 | 2 | 33 | 42.2 | 2.53 | 1.01 | 29 | 9 | 3 | 6.12 | 1.90 |
| 2007 | Toronto Blue Jays | 0 | 0 | 14 | 11.2 | 6.17 | 2.23 | 7 | 7 | 1 | 5.40 | 5.40 |
| 2008 | Toronto Blue Jays | 1 | 2 | 31 | 33.0 | 2.18 | 1.30 | 23 | 15 | 2 | 6.27 | 4.09 |
| 2009 | Toronto Blue Jays | 3 | 6 | 67 | 74.2 | 4.58 | 1.25 | 76 | 21 | 8 | 9.16 | 2.53 |
| 2010 | Seattle Mariners | 9 | 7 | 70 | 79.0 | 3.42 | 1.19 | 56 | 27 | 7 | 6.38 | 3.08 |
| 2011 | Seattle Mariners | 1 | 5 | 65 | 61.1 | 2.79 | 1.08 | 45 | 10 | 3 | 6.60 | 1.47 |
| 2012 | Seattle Mariners | 0 | 5 | 46 | 44.2 | 3.63 | 1.50 | 27 | 19 | 1 | 5.44 | 3.83 |
| 2012 | Los Angeles Dodgers | 2 | 1 | 28 | 27.1 | 2.30 | 1.13 | 27 | 14 | 0 | 8.89 | 4.61 |
| 2012 | 2 | 6 | 74 | 72.0 | 3.13 | 1.36 | 54 | 33 | 1 | 6.75 | 4.13 |
| 2013 | Los Angeles Dodgers | 6 | 4 | 58 | 54.1 | 5.30 | 1.55 | 28 | 15 | 8 | 4.64 | 2.48 |
| 2014 | Los Angeles Dodgers | 2 | 3 | 63 | 63.0 | 2.57 | 1.46 | 38 | 27 | 0 | 5.43 | 3.86 |
| Career | — | 27 | 35 | 498 | 532.0 | 3.65 | 1.33 | 375 | 185 | 41 | 6.34 | 3.13 |