| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2006 | Los Angeles Angels | 99 | 268 | 61 | 16 | 42 | 2 | 51 | 90 | .228 | .360 | .455 |
| .815 |
| 2007 | Los Angeles Angels | 75 | 219 | 54 | 10 | 34 | 5 | 33 | 63 | .247 | .351 | .443 | .794 |
| 2008 | Los Angeles Angels | 78 | 227 | 62 | 20 | 49 | 7 | 35 | 70 | .273 | .374 | .586 | .960 |
| 2009 | Los Angeles Angels | 114 | 382 | 104 | 20 | 56 | 3 | 40 | 103 | .272 | .350 | .492 | .842 |
| 2010 | Los Angeles Angels | 140 | 453 | 108 | 26 | 68 | 4 | 42 | 137 | .238 | .316 | .468 | .784 |
| 2011 | Texas Rangers | 113 | 369 | 118 | 30 | 75 | 4 | 58 | 85 | .320 | .414 | .631 | 1.045 |
| 2012 | Texas Rangers | 108 | 352 | 80 | 24 | 56 | 1 | 56 | 125 | .227 | .343 | .469 | .812 |
| 2013 | Boston Red Sox | 139 | 498 | 129 | 23 | 92 | 1 | 73 | 187 | .259 | .360 | .482 | .842 |
| 2014 | Boston Red Sox | 119 | 415 | 103 | 17 | 55 | 3 | 78 | 133 | .248 | .370 | .419 | .789 |
| 2015 | Boston Red Sox | 98 | 329 | 68 | 13 | 40 | 3 | 45 | 99 | .207 | .307 | .386 | .693 |
| 2015 | Texas Rangers | 35 | 78 | 23 | 5 | 10 | 0 | 12 | 19 | .295 | .396 | .513 | .909 |
| 2015 | 133 | 407 | 91 | 18 | 50 | 3 | 57 | 118 | .224 | .324 | .410 | .734 |
| 2016 | Cleveland Indians | 150 | 557 | 133 | 34 | 101 | 5 | 78 | 194 | .239 | .335 | .465 | .800 |
| 2017 | Texas Rangers | 124 | 425 | 82 | 29 | 66 | 1 | 49 | 163 | .193 | .285 | .428 | .713 |
| Career | — | 1,392 | 4,572 | 1,125 | 267 | 744 | 39 | 650 | 1,468 | .246 | .346 | .475 | .821 |