| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2005 | Atlanta Braves | 59 | 180 | 50 | 5 | 23 | 1 | 18 | 26 | .278 | .345 | .400 |
| .745 |
| 2006 | Atlanta Braves | 130 | 442 | 147 | 24 | 93 | 2 | 41 | 54 | .333 | .388 | .572 | .960 |
| 2007 | Atlanta Braves | 139 | 504 | 136 | 18 | 92 | 0 | 35 | 74 | .270 | .320 | .452 | .772 |
| 2008 | Atlanta Braves | 145 | 509 | 153 | 23 | 87 | 5 | 57 | 64 | .301 | .373 | .523 | .896 |
| 2009 | Atlanta Braves | 138 | 488 | 137 | 21 | 94 | 4 | 49 | 83 | .281 | .349 | .486 | .835 |
| 2010 | Atlanta Braves | 143 | 479 | 129 | 21 | 77 | 5 | 74 | 98 | .269 | .375 | .453 | .828 |
| 2011 | Atlanta Braves | 128 | 466 | 126 | 24 | 71 | 3 | 57 | 89 | .270 | .351 | .466 | .817 |
| 2012 | Atlanta Braves | 121 | 439 | 101 | 20 | 67 | 3 | 44 | 76 | .230 | .300 | .399 | .699 |
| 2013 | Atlanta Braves | 102 | 356 | 91 | 20 | 57 | 0 | 39 | 66 | .256 | .336 | .461 | .797 |
| 2014 | New York Yankees | 140 | 495 | 115 | 23 | 75 | 0 | 32 | 77 | .232 | .286 | .406 | .692 |
| 2015 | New York Yankees | 135 | 465 | 108 | 26 | 94 | 0 | 52 | 97 | .232 | .320 | .437 | .757 |
| 2016 | New York Yankees | 130 | 429 | 104 | 20 | 58 | 1 | 54 | 99 | .242 | .335 | .413 | .748 |
| 2017 | Houston Astros | 97 | 349 | 84 | 18 | 62 | 1 | 38 | 58 | .241 | .323 | .436 | .759 |
| 2018 | Houston Astros | 63 | 189 | 40 | 7 | 23 | 0 | 19 | 40 | .212 | .301 | .339 | .640 |
| 2019 | Atlanta Braves | 85 | 277 | 69 | 12 | 45 | 0 | 31 | 53 | .249 | .323 | .412 | .735 |
| Career | — | 1,755 | 6,067 | 1,590 | 282 | 1,018 | 25 | 640 | 1,054 | .262 | .337 | .452 | .789 |