| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2010 | St. Louis Cardinals | 105 | 287 | 86 | 4 | 27 | 2 | 24 | 50 | .300 | .359 | .422 |
| .781 |
| 2011 | St. Louis Cardinals | 159 | 455 | 135 | 10 | 37 | 6 | 28 | 81 | .297 | .344 | .424 | .768 |
| 2012 | St. Louis Cardinals | 117 | 443 | 135 | 4 | 40 | 19 | 34 | 71 | .305 | .373 | .400 | .773 |
| 2013 | St. Louis Cardinals | 157 | 548 | 151 | 7 | 67 | 10 | 52 | 103 | .276 | .351 | .370 | .721 |
| 2014 | St. Louis Cardinals | 140 | 413 | 125 | 3 | 46 | 6 | 28 | 78 | .303 | .372 | .378 | .750 |
| 2015 | St. Louis Cardinals | 79 | 210 | 44 | 1 | 10 | 0 | 19 | 36 | .210 | .306 | .257 | .563 |
| 2016 | San Diego Padres | 90 | 347 | 101 | 2 | 26 | 2 | 19 | 78 | .291 | .339 | .389 | .728 |
| 2017 | Chicago Cubs | 141 | 379 | 112 | 2 | 34 | 6 | 37 | 80 | .296 | .374 | .375 | .749 |
| 2018 | Kansas City Royals | 59 | 238 | 73 | 1 | 18 | 3 | 19 | 39 | .307 | .363 | .374 | .737 |
| 2018 | Arizona Diamondbacks | 84 | 289 | 68 | 2 | 22 | 1 | 14 | 56 | .235 | .304 | .325 | .629 |
| 2018 | 143 | 527 | 141 | 3 | 40 | 4 | 33 | 95 | .268 | .330 | .347 | .677 |
| 2019 | Chicago White Sox | 47 | 165 | 44 | 0 | 9 | 0 | 8 | 30 | .267 | .311 | .315 | .626 |
| 2020 | Arizona Diamondbacks | 18 | 50 | 8 | 1 | 4 | 0 | 3 | 12 | .160 | .211 | .240 | .451 |
| 2021 | Los Angeles Angels | 5 | 14 | 5 | 0 | 1 | 0 | 0 | 2 | .357 | .357 | .357 | .714 |
| Career | — | 1,201 | 3,838 | 1,087 | 37 | 341 | 55 | 285 | 716 | .283 | .348 | .373 | .721 |
