| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2012 | Oakland Athletics | 2 | 1 | 44 | 47.1 | 3.04 | 1.08 | 60 | 11 | 3 | 11.41 | 2.09 |
| 2013 |
| Oakland Athletics |
| 5 |
| 5 |
| 70 |
| 69.0 |
| 3.13 |
| 0.96 |
| 60 |
| 13 |
| 4 |
| 7.83 |
| 1.70 |
| 2014 | Oakland Athletics | 2 | 4 | 61 | 62.2 | 2.73 | 0.73 | 89 | 8 | 5 | 12.78 | 1.15 |
| 2015 | Oakland Athletics | 1 | 0 | 12 | 13.2 | 3.95 | 1.24 | 15 | 5 | 1 | 9.88 | 3.29 |
| 2016 | Oakland Athletics | 2 | 3 | 44 | 39.0 | 3.23 | 1.05 | 45 | 8 | 6 | 10.38 | 1.85 |
| 2017 | Oakland Athletics | 1 | 0 | 23 | 21.1 | 3.38 | 0.66 | 31 | 2 | 3 | 13.08 | 0.84 |
| 2017 | Washington Nationals | 1 | 0 | 30 | 30.0 | 2.40 | 1.00 | 31 | 8 | 2 | 9.30 | 2.40 |
| 2017 | 2 | 0 | 53 | 51.1 | 2.81 | 0.86 | 62 | 10 | 5 | 10.87 | 1.75 |
| 2018 | Washington Nationals | 3 | 3 | 43 | 45.0 | 1.60 | 0.60 | 60 | 6 | 3 | 12.00 | 1.20 |
| 2019 | Washington Nationals | 6 | 5 | 63 | 60.0 | 4.05 | 1.30 | 66 | 15 | 11 | 9.90 | 2.25 |
| 2020 | Washington Nationals | 0 | 2 | 11 | 7.2 | 5.87 | 1.70 | 6 | 4 | 3 | 7.04 | 4.70 |
| 2021 | Cincinnati Reds | 3 | 1 | 45 | 38.1 | 4.46 | 1.51 | 41 | 18 | 6 | 9.63 | 4.23 |
| 2021 | Seattle Mariners | 0 | 0 | 11 | 11.1 | 4.76 | 1.32 | 12 | 5 | 1 | 9.53 | 3.97 |
| 2021 | 3 | 1 | 56 | 49.2 | 4.53 | 1.47 | 53 | 23 | 7 | 9.60 | 4.17 |
| 2022 | Washington Nationals | 0 | 0 | 6 | 5.1 | 0.00 | 0.19 | 6 | 0 | 0 | 10.13 | 0.00 |
| Career | — | 26 | 24 | 463 | 450.2 | 3.20 | 1.01 | 522 | 103 | 48 | 10.42 | 2.06 |
