| Year | Team | G | AB | H | HR | RBI | SB | BB | K | AVG | OBP | SLG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011 | Milwaukee Brewers | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | .000 | .000 | .000 |
| .000 |
| 2012 | Milwaukee Brewers | 78 | 233 | 62 | 8 | 30 | 1 | 17 | 56 | .266 | .321 | .408 | .729 |
| 2013 | Milwaukee Brewers | 67 | 183 | 31 | 4 | 22 | 0 | 13 | 53 | .169 | .236 | .284 | .520 |
| 2014 | Milwaukee Brewers | 52 | 111 | 26 | 4 | 16 | 0 | 11 | 32 | .234 | .320 | .387 | .707 |
| 2015 | Milwaukee Brewers | 79 | 229 | 48 | 4 | 22 | 0 | 23 | 65 | .210 | .282 | .293 | .575 |
| 2016 | Milwaukee Brewers | 76 | 208 | 42 | 8 | 21 | 1 | 35 | 56 | .202 | .332 | .351 | .683 |
| 2017 | Los Angeles Angels | 138 | 429 | 95 | 14 | 38 | 0 | 15 | 119 | .221 | .276 | .368 | .644 |
| 2018 | Los Angeles Angels | 78 | 265 | 59 | 5 | 32 | 0 | 13 | 73 | .223 | .284 | .332 | .616 |
| 2018 | Houston Astros | 41 | 108 | 25 | 4 | 12 | 0 | 3 | 25 | .231 | .257 | .398 | .655 |
| 2018 | 119 | 373 | 84 | 9 | 44 | 0 | 16 | 98 | .225 | .276 | .351 | .627 |
| 2019 | Kansas City Royals | 74 | 238 | 54 | 6 | 17 | 0 | 17 | 55 | .227 | .291 | .366 | .657 |
| 2019 | Chicago Cubs | 4 | 11 | 0 | 0 | 0 | 0 | 2 | 5 | .000 | .154 | .000 | .154 |
| 2019 | Houston Astros | 27 | 84 | 17 | 6 | 10 | 0 | 13 | 26 | .202 | .316 | .464 | .780 |
| 2019 | 105 | 333 | 71 | 12 | 27 | 0 | 32 | 86 | .213 | .293 | .378 | .671 |
| 2020 | Houston Astros | 47 | 135 | 29 | 6 | 24 | 1 | 27 | 51 | .215 | .350 | .378 | .728 |
| 2021 | Houston Astros | 125 | 373 | 64 | 12 | 36 | 0 | 47 | 127 | .172 | .272 | .300 | .572 |
| 2022 | Houston Astros | 113 | 344 | 64 | 15 | 45 | 0 | 22 | 116 | .186 | .248 | .352 | .600 |
| 2023 | Houston Astros | 117 | 362 | 69 | 15 | 36 | 0 | 30 | 139 | .191 | .258 | .348 | .606 |
| 2024 | Chicago White Sox | 48 | 135 | 16 | 4 | 11 | 0 | 8 | 51 | .119 | .174 | .230 | .404 |
| 2025 | San Diego Padres | 64 | 147 | 30 | 4 | 12 | 0 | 8 | 57 | .204 | .245 | .327 | .572 |
| Career | — | 1,231 | 3,596 | 731 | 119 | 384 | 3 | 304 | 1,107 | .203 | .277 | .343 | .620 |
