| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2008 | Los Angeles Dodgers | 5 | 5 | 22 | 107.2 | 4.26 | 1.50 | 100 | 52 | 11 | 8.36 | 4.35 |
| 2009 |
| Los Angeles Dodgers |
| 8 |
| 8 |
| 31 |
| 171.0 |
| 2.79 |
| 1.23 |
| 185 |
| 91 |
| 7 |
| 9.74 |
| 4.79 |
| 2010 | Los Angeles Dodgers | 13 | 10 | 32 | 204.1 | 2.91 | 1.18 | 212 | 81 | 13 | 9.34 | 3.57 |
| 2011 | Los Angeles Dodgers | 21 | 5 | 33 | 233.1 | 2.28 | 0.98 | 248 | 54 | 15 | 9.57 | 2.08 |
| 2012 | Los Angeles Dodgers | 14 | 9 | 33 | 227.2 | 2.53 | 1.02 | 229 | 63 | 16 | 9.05 | 2.49 |
| 2013 | Los Angeles Dodgers | 16 | 9 | 33 | 236.0 | 1.83 | 0.92 | 232 | 52 | 11 | 8.85 | 1.98 |
| 2014 | Los Angeles Dodgers | 21 | 3 | 27 | 198.1 | 1.77 | 0.86 | 239 | 31 | 9 | 10.85 | 1.41 |
| 2015 | Los Angeles Dodgers | 16 | 7 | 33 | 232.2 | 2.13 | 0.88 | 301 | 42 | 15 | 11.64 | 1.62 |
| 2016 | Los Angeles Dodgers | 12 | 4 | 21 | 149.0 | 1.69 | 0.72 | 172 | 11 | 8 | 10.39 | 0.66 |
| 2017 | Los Angeles Dodgers | 18 | 4 | 27 | 175.0 | 2.31 | 0.95 | 202 | 30 | 23 | 10.39 | 1.54 |
| 2018 | Los Angeles Dodgers | 9 | 5 | 26 | 161.1 | 2.73 | 1.04 | 155 | 29 | 17 | 8.65 | 1.62 |
| 2019 | Los Angeles Dodgers | 16 | 5 | 29 | 178.1 | 3.03 | 1.04 | 189 | 41 | 28 | 9.54 | 2.07 |
| 2020 | Los Angeles Dodgers | 6 | 2 | 10 | 58.1 | 2.16 | 0.84 | 62 | 8 | 8 | 9.57 | 1.23 |
| 2021 | Los Angeles Dodgers | 10 | 8 | 22 | 121.2 | 3.55 | 1.02 | 144 | 21 | 15 | 10.65 | 1.55 |
| 2022 | Los Angeles Dodgers | 12 | 3 | 22 | 126.1 | 2.28 | 0.94 | 137 | 23 | 10 | 9.76 | 1.64 |
| 2023 | Los Angeles Dodgers | 13 | 5 | 24 | 131.2 | 2.46 | 1.06 | 137 | 40 | 19 | 9.36 | 2.73 |
| 2024 | Los Angeles Dodgers | 2 | 2 | 7 | 30.0 | 4.50 | 1.50 | 24 | 9 | 2 | 7.20 | 2.70 |
| 2025 | Los Angeles Dodgers | 11 | 2 | 23 | 112.2 | 3.36 | 1.22 | 84 | 35 | 8 | 6.71 | 2.80 |
| Career | — | 223 | 96 | 455 | 2855.1 | 2.53 | 1.02 | 3,052 | 713 | 235 | 9.62 | 2.25 |