| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2010 | St. Louis Cardinals | 0 | 0 | 27 | 30.2 | 3.52 | 1.40 | 29 | 15 | 4 | 8.51 | 4.40 |
| 2011 |
| St. Louis Cardinals |
| 5 |
| 6 |
| 68 |
| 75.0 |
| 2.28 |
| 0.95 |
| 75 |
| 21 |
| 7 |
| 9.00 |
| 2.52 |
| 2012 | St. Louis Cardinals | 1 | 4 | 65 | 58.2 | 4.30 | 1.41 | 60 | 27 | 5 | 9.20 | 4.14 |
| 2013 | St. Louis Cardinals | 0 | 3 | 27 | 28.0 | 4.50 | 1.18 | 22 | 6 | 3 | 7.07 | 1.93 |
| 2014 | Los Angeles Angels | 5 | 0 | 57 | 58.2 | 3.38 | 1.09 | 61 | 14 | 5 | 9.36 | 2.15 |
| 2015 | Los Angeles Angels | 5 | 2 | 72 | 63.2 | 4.24 | 1.15 | 74 | 12 | 8 | 10.46 | 1.70 |
| 2016 | Los Angeles Angels | 3 | 6 | 58 | 56.1 | 4.47 | 1.26 | 45 | 19 | 9 | 7.19 | 3.04 |
| 2016 | New York Mets | 0 | 1 | 17 | 17.1 | 2.08 | 0.63 | 19 | 0 | 3 | 9.87 | 0.00 |
| 2016 | 3 | 7 | 75 | 73.2 | 3.91 | 1.11 | 64 | 19 | 12 | 7.82 | 2.32 |
| 2017 | New York Mets | 1 | 2 | 48 | 45.0 | 6.00 | 1.78 | 47 | 20 | 7 | 9.40 | 4.00 |
| 2017 | Los Angeles Angels | 1 | 0 | 13 | 13.2 | 2.63 | 0.66 | 9 | 2 | 0 | 5.93 | 1.32 |
| 2017 | 2 | 2 | 61 | 58.2 | 5.22 | 1.52 | 56 | 22 | 7 | 8.59 | 3.38 |
| 2018 | Arizona Diamondbacks | 4 | 4 | 41 | 40.0 | 4.50 | 1.33 | 30 | 13 | 5 | 6.75 | 2.93 |
| 2019 | Philadelphia Phillies | 0 | 0 | 3 | 2.2 | 6.75 | 3.00 | 3 | 0 | 1 | 10.13 | 0.00 |
| Career | — | 25 | 28 | 496 | 489.2 | 3.91 | 1.22 | 474 | 149 | 57 | 8.71 | 2.74 |
