| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2007 | San Diego Padres | 2 | 2 | 22 | 21.0 | 1.29 | 0.90 | 16 | 6 | 1 | 6.86 | 2.57 |
| 2008 |
| San Diego Padres |
| 0 |
| 4 |
| 25 |
| 25.2 |
| 8.42 |
| 2.14 |
| 17 |
| 13 |
| 4 |
| 5.96 |
| 4.56 |
| 2009 | San Diego Padres | 1 | 0 | 52 | 45.0 | 2.80 | 1.22 | 55 | 18 | 2 | 11.00 | 3.60 |
| 2010 | San Diego Padres | 1 | 0 | 65 | 35.0 | 1.29 | 0.86 | 45 | 7 | 1 | 11.57 | 1.80 |
| 2011 | San Diego Padres | 0 | 0 | 18 | 10.0 | 4.50 | 1.50 | 9 | 7 | 1 | 8.10 | 6.30 |
| 2012 | San Diego Padres | 1 | 4 | 55 | 31.2 | 3.41 | 1.39 | 39 | 14 | 2 | 11.08 | 3.98 |
| 2013 | San Diego Padres | 3 | 1 | 50 | 30.0 | 2.10 | 1.07 | 29 | 4 | 3 | 8.70 | 1.20 |
| 2013 | Arizona Diamondbacks | 0 | 1 | 22 | 9.1 | 6.75 | 1.93 | 7 | 6 | 1 | 6.75 | 5.79 |
| 2013 | 3 | 2 | 72 | 39.1 | 3.20 | 1.27 | 36 | 10 | 4 | 8.24 | 2.29 |
| 2014 | Arizona Diamondbacks | 1 | 0 | 37 | 24.0 | 2.63 | 1.08 | 25 | 3 | 3 | 9.38 | 1.13 |
| 2014 | Los Angeles Angels | 1 | 1 | 16 | 6.1 | 8.53 | 2.21 | 2 | 1 | 0 | 2.84 | 1.42 |
| 2014 | 2 | 1 | 53 | 30.1 | 3.86 | 1.32 | 27 | 4 | 3 | 8.01 | 1.19 |
| 2015 | Houston Astros | 1 | 3 | 43 | 22.2 | 3.18 | 1.54 | 26 | 12 | 1 | 10.32 | 4.76 |
| Career | — | 11 | 16 | 405 | 260.2 | 3.38 | 1.32 | 270 | 91 | 19 | 9.32 | 3.14 |
