| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | San Francisco Giants | 1 | 0 | 9 | 7.0 | 0.00 | 0.71 | 9 | 0 | 0 | 11.57 | 0.00 |
| 2015 |
| San Francisco Giants |
| 3 |
| 3 |
| 55 |
| 51.1 |
| 2.45 |
| 0.86 |
| 50 |
| 10 |
| 4 |
| 8.77 |
| 1.75 |
| 2016 | San Francisco Giants | 3 | 3 | 72 | 61.0 | 3.10 | 1.13 | 57 | 19 | 4 | 8.41 | 2.80 |
| 2017 | San Francisco Giants | 4 | 3 | 68 | 61.1 | 2.64 | 1.43 | 58 | 29 | 4 | 8.51 | 4.26 |
| 2018 | San Francisco Giants | 3 | 5 | 49 | 45.1 | 3.97 | 1.41 | 37 | 21 | 5 | 7.35 | 4.17 |
| 2019 | Seattle Mariners | 0 | 1 | 4 | 3.1 | 8.10 | 0.60 | 3 | 0 | 1 | 8.10 | 0.00 |
| 2019 | Washington Nationals | 2 | 0 | 24 | 21.0 | 5.14 | 1.33 | 15 | 8 | 5 | 6.43 | 3.43 |
| 2019 | 2 | 1 | 28 | 24.1 | 5.55 | 1.23 | 18 | 8 | 6 | 6.66 | 2.96 |
| 2020 | New York Mets | 0 | 1 | 4 | 3.1 | 8.10 | 1.80 | 4 | 1 | 0 | 10.80 | 2.70 |
| 2021 | Tampa Bay Rays | 0 | 0 | 13 | 16.0 | 1.69 | 1.25 | 16 | 6 | 1 | 9.00 | 3.38 |
| 2021 | Los Angeles Angels | 0 | 0 | 9 | 6.1 | 9.95 | 2.37 | 4 | 4 | 3 | 5.68 | 5.68 |
| 2021 | Milwaukee Brewers | 3 | 2 | 35 | 36.1 | 1.73 | 0.91 | 38 | 12 | 4 | 9.41 | 2.97 |
| 2021 | 3 | 2 | 57 | 58.2 | 2.61 | 1.16 | 58 | 22 | 8 | 8.90 | 3.38 |
| 2022 | Cincinnati Reds | 3 | 3 | 66 | 62.1 | 4.91 | 1.51 | 60 | 33 | 8 | 8.66 | 4.76 |
| 2024 | Los Angeles Angels | 3 | 2 | 72 | 73.1 | 3.31 | 1.09 | 57 | 24 | 10 | 7.00 | 2.95 |
| 2025 | Los Angeles Angels | 1 | 2 | 19 | 22.0 | 3.27 | 1.23 | 14 | 10 | 2 | 5.73 | 4.09 |
| Career | — | 26 | 25 | 499 | 470.0 | 3.39 | 1.22 | 422 | 177 | 51 | 8.08 | 3.39 |
