| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011 | Atlanta Braves | 1 | 1 | 5 | 19.2 | 5.03 | 1.47 | 10 | 8 | 4 | 4.58 | 3.66 |
| 2012 |
| Atlanta Braves |
| 0 |
| 0 |
| 2 |
| 6.1 |
| 5.68 |
| 0.95 |
| 5 |
| 1 |
| 0 |
| 7.11 |
| 1.42 |
| 2013 | Atlanta Braves | 14 | 8 | 30 | 185.2 | 3.20 | 1.17 | 170 | 45 | 22 | 8.24 | 2.18 |
| 2014 | Atlanta Braves | 14 | 13 | 33 | 221.0 | 2.89 | 1.08 | 186 | 51 | 22 | 7.57 | 2.08 |
| 2015 | Atlanta Braves | 11 | 8 | 33 | 200.2 | 4.04 | 1.31 | 171 | 73 | 27 | 7.67 | 3.27 |
| 2016 | Atlanta Braves | 7 | 10 | 30 | 188.0 | 3.21 | 1.05 | 167 | 41 | 22 | 7.99 | 1.96 |
| 2017 | Atlanta Braves | 11 | 13 | 32 | 188.1 | 4.49 | 1.37 | 151 | 72 | 31 | 7.22 | 3.44 |
| 2018 | Atlanta Braves | 9 | 9 | 31 | 175.2 | 3.94 | 1.17 | 162 | 84 | 26 | 8.30 | 4.30 |
| 2019 | Atlanta Braves | 10 | 11 | 33 | 174.2 | 3.81 | 1.32 | 162 | 83 | 22 | 8.35 | 4.28 |
| 2020 | Los Angeles Angels | 0 | 4 | 10 | 31.1 | 10.05 | 1.76 | 20 | 16 | 12 | 5.74 | 4.60 |
| 2021 | Detroit Tigers | 1 | 0 | 1 | 5.0 | 1.80 | 1.40 | 3 | 3 | 1 | 5.40 | 5.40 |
| 2023 | Milwaukee Brewers | 3 | 5 | 14 | 71.2 | 4.40 | 1.13 | 50 | 13 | 13 | 6.28 | 1.63 |
| 2024 | New York Mets | 0 | 0 | 1 | 2.2 | 13.50 | 3.00 | 3 | 2 | 1 | 10.13 | 6.75 |
| Career | — | 81 | 82 | 255 | 1470.2 | 3.85 | 1.22 | 1,260 | 492 | 203 | 7.71 | 3.01 |
