| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2012 | Seattle Mariners | 1 | 3 | 16 | 59.0 | 3.36 | 1.00 | 48 | 12 | 6 | 7.32 | 1.83 |
| 2013 | Seattle Mariners |
| 5 |
| 3 |
| 14 |
| 72.1 |
| 4.98 |
| 1.45 |
| 57 |
| 26 |
| 12 |
| 7.09 |
| 3.24 |
| 2014 | Seattle Mariners | 1 | 6 | 17 | 75.1 | 5.26 | 1.54 | 60 | 34 | 13 | 7.17 | 4.06 |
| 2015 | Tampa Bay Rays | 11 | 6 | 34 | 163.1 | 3.75 | 1.13 | 126 | 40 | 16 | 6.94 | 2.20 |
| 2016 | Tampa Bay Rays | 7 | 11 | 64 | 90.2 | 3.77 | 1.28 | 63 | 26 | 14 | 6.25 | 2.58 |
| 2017 | Tampa Bay Rays | 4 | 3 | 26 | 69.1 | 4.80 | 1.18 | 55 | 16 | 10 | 7.14 | 2.08 |
| 2017 | Seattle Mariners | 1 | 3 | 11 | 62.0 | 3.92 | 1.16 | 54 | 15 | 12 | 7.84 | 2.18 |
| 2017 | 2 teams | 5 | 6 | 37 | 131.1 | 4.39 | 1.17 | 109 | 31 | 22 | 7.47 | 2.12 |
| 2018 | Seattle Mariners | 2 | 4 | 10 | 45.2 | 6.50 | 1.40 | 33 | 12 | 14 | 6.50 | 2.36 |
| 2019 | Boston Red Sox | 0 | 0 | 1 | 3.0 | 12.00 | 1.67 | 1 | 1 | 2 | 3.00 | 3.00 |
| 2020 | New York Mets | 0 | 0 | 6 | 14.1 | 0.63 | 0.84 | 9 | 4 | 1 | 5.65 | 2.51 |
| 2021 | Detroit Tigers | 1 | 1 | 17 | 26.2 | 5.74 | 1.09 | 20 | 5 | 4 | 6.75 | 1.69 |
| 2022 | Washington Nationals | 4 | 2 | 60 | 86.1 | 2.92 | 1.08 | 61 | 14 | 11 | 6.36 | 1.46 |
| 2023 | Washington Nationals | 2 | 3 | 23 | 27.0 | 6.33 | 1.56 | 13 | 6 | 4 | 4.33 | 2.00 |
| 2023 | Tampa Bay Rays | 1 | 0 | 15 | 33.1 | 6.48 | 1.59 | 30 | 7 | 7 | 8.10 | 1.89 |
| 2023 | 2 teams | 3 | 3 | 38 | 60.1 | 6.41 | 1.57 | 43 | 13 | 11 | 6.41 | 1.94 |
| 2024 | Tampa Bay Rays | 3 | 0 | 13 | 20.2 | 4.35 | 1.06 | 15 | 10 | 5 | 6.53 | 4.35 |
| 2025 | Minnesota Twins | 0 | 1 | 9 | 11.0 | 2.45 | 1.09 | 5 | 2 | 2 | 4.09 | 1.64 |
| Career | — | 43 | 46 | 336 | 860.0 | 4.34 | 1.24 | 650 | 230 | 133 | 6.80 | 2.41 |
