| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2013 | Seattle Mariners | 3 | 0 | 4 | 24.0 | 1.50 | 0.92 | 21 | 7 | 2 | 7.88 | 2.63 |
| 2014 |
| Seattle Mariners |
| 6 |
| 4 |
| 13 |
| 74.0 |
| 3.04 |
| 1.20 |
| 59 |
| 29 |
| 3 |
| 7.18 |
| 3.53 |
| 2015 | Seattle Mariners | 3 | 4 | 13 | 67.0 | 3.90 | 1.43 | 56 | 29 | 8 | 7.52 | 3.90 |
| 2016 | Seattle Mariners | 6 | 7 | 20 | 121.0 | 3.79 | 1.31 | 117 | 24 | 9 | 8.70 | 1.79 |
| 2017 | Seattle Mariners | 12 | 5 | 24 | 136.0 | 2.98 | 1.10 | 156 | 37 | 9 | 10.32 | 2.45 |
| 2018 | Seattle Mariners | 11 | 6 | 28 | 160.1 | 3.76 | 1.10 | 208 | 42 | 23 | 11.68 | 2.36 |
| 2019 | New York Yankees | 15 | 6 | 29 | 150.2 | 3.82 | 1.28 | 186 | 55 | 23 | 11.11 | 3.29 |
| 2020 | New York Yankees | 1 | 1 | 5 | 20.1 | 6.64 | 1.48 | 26 | 7 | 4 | 11.51 | 3.10 |
| 2021 | Seattle Mariners | 0 | 0 | 1 | 1.1 | 6.75 | 0.75 | 2 | 1 | 0 | 13.50 | 6.75 |
| 2023 | Boston Red Sox | 7 | 5 | 19 | 96.0 | 4.50 | 1.31 | 101 | 33 | 18 | 9.47 | 3.09 |
| 2024 | Los Angeles Dodgers | 8 | 2 | 18 | 89.1 | 4.43 | 1.46 | 64 | 48 | 11 | 6.45 | 4.84 |
| 2024 | Boston Red Sox | 1 | 1 | 3 | 11.0 | 4.09 | 1.36 | 9 | 2 | 1 | 7.36 | 1.64 |
| 2024 | 9 | 3 | 21 | 100.1 | 4.40 | 1.45 | 73 | 50 | 12 | 6.55 | 4.49 |
| Career | — | 73 | 41 | 177 | 951.0 | 3.77 | 1.25 | 1,005 | 314 | 111 | 9.51 | 2.97 |
