| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | Colorado Rockies | 2 | 1 | 54 | 68.2 | 4.19 | 1.19 | 63 | 31 | 7 | 8.26 | 4.06 |
| 2015 | Colorado Rockies |
| 0 |
| 1 |
| 36 |
| 33.1 |
| 4.86 |
| 1.77 |
| 39 |
| 28 |
| 3 |
| 10.53 |
| 7.56 |
| 2016 | Chicago White Sox | 0 | 1 | 29 | 27.1 | 2.63 | 1.50 | 25 | 20 | 2 | 8.23 | 6.59 |
| 2017 | Chicago White Sox | 1 | 3 | 37 | 36.0 | 2.50 | 0.97 | 60 | 7 | 3 | 15.00 | 1.75 |
| 2017 | New York Yankees | 1 | 1 | 32 | 26.2 | 2.70 | 1.31 | 36 | 10 | 1 | 12.15 | 3.38 |
| 2017 | 2 teams | 2 | 4 | 69 | 62.2 | 2.59 | 1.12 | 96 | 17 | 4 | 13.79 | 2.44 |
| 2018 | New York Yankees | 2 | 0 | 24 | 23.1 | 6.56 | 1.63 | 30 | 15 | 3 | 11.57 | 5.79 |
| 2019 | New York Yankees | 3 | 2 | 72 | 61.1 | 3.67 | 1.06 | 88 | 20 | 9 | 12.91 | 2.93 |
| 2020 | New York Yankees | 0 | 0 | 1 | 1.0 | 0.00 | 2.00 | 3 | 1 | 0 | 27.00 | 9.00 |
| 2022 | Los Angeles Dodgers | 0 | 0 | 13 | 12.2 | 2.84 | 0.63 | 14 | 3 | 2 | 9.95 | 2.13 |
| 2023 | New York Yankees | 1 | 3 | 42 | 40.2 | 2.66 | 1.11 | 48 | 19 | 5 | 10.62 | 4.20 |
| 2024 | New York Yankees | 0 | 2 | 50 | 42.2 | 2.11 | 1.15 | 46 | 19 | 5 | 9.70 | 4.01 |
| 2025 | Detroit Tigers | 1 | 5 | 66 | 63.0 | 4.43 | 1.30 | 50 | 31 | 8 | 7.14 | 4.43 |
| Career | — | 11 | 19 | 456 | 436.2 | 3.61 | 1.24 | 502 | 204 | 48 | 10.35 | 4.20 |
