| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | St. Louis Cardinals | 4 | 2 | 10 | 34.2 | 4.15 | 1.53 | 31 | 21 | 4 | 8.05 | 5.45 |
| 2015 | St. Louis Cardinals |
| 0 |
| 0 |
| 1 |
| 2.2 |
| 13.50 |
| 3.00 |
| 1 |
| 1 |
| 1 |
| 3.38 |
| 3.38 |
| 2017 | St. Louis Cardinals | 0 | 0 | 1 | 3.1 | 13.50 | 1.80 | 2 | 0 | 3 | 5.40 | 0.00 |
| 2017 | Seattle Mariners | 1 | 1 | 10 | 36.2 | 5.40 | 1.75 | 30 | 11 | 5 | 7.36 | 2.70 |
| 2017 | 2 teams | 1 | 1 | 11 | 40.0 | 6.08 | 1.75 | 32 | 11 | 8 | 7.20 | 2.48 |
| 2018 | Seattle Mariners | 13 | 9 | 29 | 166.2 | 4.00 | 1.22 | 145 | 32 | 17 | 7.83 | 1.73 |
| 2019 | Seattle Mariners | 16 | 13 | 34 | 203.0 | 3.99 | 1.31 | 147 | 56 | 23 | 6.52 | 2.48 |
| 2020 | Seattle Mariners | 7 | 2 | 11 | 69.2 | 3.10 | 0.95 | 64 | 7 | 8 | 8.27 | 0.90 |
| 2021 | Seattle Mariners | 10 | 6 | 25 | 143.1 | 3.96 | 1.17 | 108 | 42 | 29 | 6.78 | 2.64 |
| 2022 | Seattle Mariners | 10 | 15 | 32 | 183.0 | 4.13 | 1.33 | 103 | 50 | 30 | 5.07 | 2.46 |
| 2023 | Seattle Mariners | 4 | 1 | 10 | 50.0 | 5.22 | 1.46 | 34 | 18 | 5 | 6.12 | 3.24 |
| 2024 | Pittsburgh Pirates | 1 | 1 | 7 | 33.2 | 4.54 | 1.60 | 23 | 11 | 5 | 6.15 | 2.94 |
| Career | — | 66 | 50 | 170 | 926.2 | 4.16 | 1.30 | 688 | 249 | 130 | 6.68 | 2.42 |
