| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017 | St. Louis Cardinals | 0 | 0 | 50 | 51.2 | 2.44 | 0.93 | 51 | 11 | 8 | 8.88 | 1.92 |
| 2018 | St. Louis Cardinals |
| 3 |
| 3 |
| 45 |
| 50.2 |
| 3.20 |
| 1.16 |
| 60 |
| 16 |
| 5 |
| 10.66 |
| 2.84 |
| 2019 | St. Louis Cardinals | 3 | 4 | 66 | 72.2 | 3.59 | 1.18 | 87 | 27 | 6 | 10.78 | 3.34 |
| 2021 | San Francisco Giants | 0 | 1 | 18 | 18.1 | 5.89 | 1.58 | 22 | 4 | 4 | 10.80 | 1.96 |
| 2022 | San Francisco Giants | 6 | 2 | 76 | 68.0 | 3.18 | 1.31 | 54 | 18 | 5 | 7.15 | 2.38 |
| 2023 | San Francisco Giants | 3 | 5 | 40 | 38.1 | 3.99 | 1.17 | 47 | 14 | 6 | 11.03 | 3.29 |
| 2024 | Chicago White Sox | 0 | 6 | 54 | 48.2 | 6.29 | 1.42 | 58 | 17 | 9 | 10.73 | 3.14 |
| 2024 | Atlanta Braves | 0 | 0 | 5 | 6.2 | 2.70 | 0.90 | 9 | 2 | 2 | 12.15 | 2.70 |
| 2024 | 2 teams | 0 | 6 | 59 | 55.1 | 5.86 | 1.36 | 67 | 19 | 11 | 10.90 | 3.09 |
| 2025 | Detroit Tigers | 1 | 0 | 19 | 18.2 | 7.71 | 1.77 | 20 | 11 | 3 | 9.64 | 5.30 |
| 2025 | Atlanta Braves | 0 | 1 | 3 | 4.2 | 7.71 | 1.50 | 6 | 1 | 2 | 11.57 | 1.93 |
| 2025 | 2 teams | 1 | 1 | 22 | 23.1 | 7.71 | 1.71 | 26 | 12 | 5 | 10.03 | 4.63 |
| Career | — | 16 | 22 | 376 | 378.1 | 4.04 | 1.24 | 414 | 121 | 50 | 9.85 | 2.88 |