| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | Arizona Diamondbacks | 0 | 1 | 3 | 14.0 | 3.86 | 1.50 | 10 | 8 | 0 | 6.43 | 5.14 |
| 2015 | Arizona Diamondbacks |
| 5 |
| 1 |
| 66 |
| 75.0 |
| 2.76 |
| 1.15 |
| 58 |
| 30 |
| 3 |
| 6.96 |
| 3.60 |
| 2016 | Arizona Diamondbacks | 0 | 1 | 32 | 22.2 | 6.75 | 1.46 | 28 | 11 | 1 | 11.12 | 4.37 |
| 2017 | Arizona Diamondbacks | 1 | 0 | 71 | 51.1 | 3.51 | 1.34 | 61 | 21 | 5 | 10.69 | 3.68 |
| 2018 | Arizona Diamondbacks | 1 | 6 | 77 | 49.1 | 3.10 | 1.34 | 53 | 25 | 0 | 9.67 | 4.56 |
| 2019 | Arizona Diamondbacks | 2 | 2 | 77 | 52.2 | 3.76 | 1.33 | 68 | 18 | 6 | 11.62 | 3.08 |
| 2020 | Arizona Diamondbacks | 1 | 1 | 11 | 6.2 | 8.10 | 1.95 | 10 | 4 | 1 | 13.50 | 5.40 |
| 2020 | Chicago Cubs | 0 | 1 | 4 | 3.0 | 3.00 | 1.00 | 3 | 1 | 1 | 9.00 | 3.00 |
| 2020 | 2 teams | 1 | 2 | 15 | 9.2 | 6.52 | 1.66 | 13 | 5 | 2 | 12.10 | 4.66 |
| 2021 | Chicago Cubs | 0 | 2 | 43 | 39.1 | 2.06 | 0.84 | 37 | 12 | 1 | 8.47 | 2.75 |
| 2021 | Oakland Athletics | 2 | 2 | 28 | 29.1 | 1.53 | 1.06 | 27 | 7 | 3 | 8.28 | 2.15 |
| 2021 | 2 teams | 2 | 4 | 71 | 68.2 | 1.83 | 0.93 | 64 | 19 | 4 | 8.39 | 2.49 |
| 2022 | Detroit Tigers | 2 | 3 | 64 | 57.1 | 2.83 | 1.17 | 67 | 19 | 5 | 10.52 | 2.98 |
| 2023 | Arizona Diamondbacks | 2 | 3 | 43 | 34.1 | 4.19 | 1.43 | 49 | 18 | 3 | 12.84 | 4.72 |
| 2023 | Milwaukee Brewers | 1 | 1 | 20 | 17.0 | 5.82 | 1.41 | 14 | 10 | 3 | 7.41 | 5.29 |
| 2023 | 2 teams | 3 | 4 | 63 | 51.1 | 4.73 | 1.42 | 63 | 28 | 6 | 11.05 | 4.91 |
| 2024 | Detroit Tigers | 3 | 2 | 41 | 37.0 | 3.16 | 1.38 | 50 | 16 | 2 | 12.16 | 3.89 |
| 2024 | Texas Rangers | 1 | 1 | 21 | 19.1 | 4.19 | 1.66 | 20 | 15 | 3 | 9.31 | 6.98 |
| 2024 | 2 teams | 4 | 3 | 62 | 56.1 | 3.51 | 1.47 | 70 | 31 | 5 | 11.18 | 4.95 |
| 2025 | Washington Nationals | 1 | 1 | 26 | 20.0 | 2.70 | 1.60 | 18 | 12 | 1 | 8.10 | 5.40 |
| 2025 | Los Angeles Angels | 0 | 0 | 16 | 13.2 | 1.98 | 1.17 | 18 | 7 | 1 | 11.85 | 4.61 |
| 2025 | 2 teams | 1 | 1 | 42 | 33.2 | 2.41 | 1.43 | 36 | 19 | 2 | 9.62 | 5.08 |
| Career | — | 22 | 28 | 643 | 542.0 | 3.35 | 1.28 | 591 | 234 | 39 | 9.81 | 3.89 |
