| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | New York Mets | 1 | 3 | 10 | 44.1 | 4.06 | 1.51 | 42 | 23 | 8 | 8.53 | 4.67 |
| 2015 | New York Mets |
| 0 |
| 1 |
| 5 |
| 10.0 |
| 4.50 |
| 1.40 |
| 13 |
| 5 |
| 0 |
| 11.70 |
| 4.50 |
| 2016 | New York Mets | 0 | 1 | 9 | 19.0 | 8.05 | 2.05 | 20 | 16 | 4 | 9.47 | 7.58 |
| 2017 | New York Mets | 5 | 11 | 34 | 119.0 | 5.52 | 1.75 | 114 | 67 | 12 | 8.62 | 5.07 |
| 2019 | Texas Rangers | 2 | 0 | 22 | 29.0 | 2.48 | 0.97 | 34 | 5 | 5 | 10.55 | 1.55 |
| 2020 | Texas Rangers | 0 | 1 | 17 | 17.2 | 4.08 | 1.02 | 19 | 6 | 2 | 9.68 | 3.06 |
| 2021 | Seattle Mariners | 5 | 3 | 40 | 43.1 | 7.27 | 1.64 | 37 | 15 | 4 | 7.68 | 3.12 |
| 2021 | Houston Astros | 0 | 1 | 4 | 6.0 | 0.00 | 0.83 | 5 | 2 | 0 | 7.50 | 3.00 |
| 2021 | 2 teams | 5 | 4 | 44 | 49.1 | 6.39 | 1.54 | 42 | 17 | 4 | 7.66 | 3.10 |
| 2022 | Houston Astros | 5 | 2 | 71 | 68.1 | 2.37 | 1.02 | 73 | 23 | 3 | 9.61 | 3.03 |
| 2023 | Houston Astros | 3 | 3 | 68 | 67.1 | 5.08 | 1.53 | 79 | 29 | 11 | 10.56 | 3.88 |
| 2024 | Houston Astros | 1 | 2 | 41 | 38.1 | 4.70 | 1.41 | 23 | 19 | 8 | 5.40 | 4.46 |
| 2025 | Houston Astros | 0 | 0 | 3 | 4.0 | 4.50 | 1.25 | 5 | 2 | 0 | 11.25 | 4.50 |
| 2025 | Atlanta Braves | 0 | 1 | 36 | 34.1 | 5.50 | 1.40 | 34 | 21 | 3 | 8.91 | 5.50 |
| 2025 | Detroit Tigers | 1 | 1 | 20 | 22.0 | 2.86 | 1.18 | 19 | 14 | 2 | 7.77 | 5.73 |
| 2025 | 3 teams | 1 | 2 | 59 | 60.1 | 4.48 | 1.31 | 58 | 37 | 5 | 8.65 | 5.52 |
| Career | — | 23 | 30 | 380 | 522.2 | 4.68 | 1.45 | 517 | 247 | 62 | 8.90 | 4.25 |
