| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016 | Chicago White Sox | 0 | 2 | 8 | 11.2 | 8.49 | 1.63 | 10 | 7 | 2 | 7.71 | 5.40 |
| 2017 | Chicago White Sox |
| 3 |
| 1 |
| 7 |
| 23.1 |
| 3.86 |
| 1.24 |
| 19 |
| 13 |
| 4 |
| 7.33 |
| 5.01 |
| 2018 | Chicago White Sox | 2 | 4 | 9 | 32.1 | 8.07 | 1.89 | 29 | 24 | 8 | 8.07 | 6.68 |
| 2019 | Chicago White Sox | 1 | 2 | 20 | 27.1 | 6.26 | 1.68 | 25 | 20 | 5 | 8.23 | 6.59 |
| 2020 | Detroit Tigers | 0 | 0 | 7 | 6.2 | 6.75 | 1.65 | 7 | 3 | 1 | 9.45 | 4.05 |
| 2020 | Baltimore Orioles | 0 | 0 | 3 | 3.2 | 0.00 | 0.55 | 4 | 2 | 0 | 9.82 | 4.91 |
| 2020 | 2 teams | 0 | 0 | 10 | 10.1 | 4.35 | 1.26 | 11 | 5 | 1 | 9.58 | 4.35 |
| 2021 | Cincinnati Reds | 0 | 0 | 20 | 25.2 | 6.66 | 1.52 | 24 | 13 | 3 | 8.42 | 4.56 |
| 2023 | Los Angeles Angels | 1 | 1 | 3 | 10.0 | 2.70 | 1.00 | 6 | 4 | 1 | 5.40 | 3.60 |
| 2024 | Los Angeles Angels | 0 | 5 | 37 | 86.2 | 4.15 | 1.40 | 81 | 40 | 11 | 8.41 | 4.15 |
| 2025 | Los Angeles Angels | 0 | 0 | 13 | 29.1 | 5.83 | 1.23 | 26 | 11 | 5 | 7.98 | 3.38 |
| Career | — | 7 | 15 | 127 | 256.2 | 5.44 | 1.46 | 231 | 137 | 40 | 8.10 | 4.80 |