| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016 | Minnesota Twins | 3 | 7 | 14 | 58.1 | 8.02 | 1.87 | 49 | 35 | 12 | 7.56 | 5.40 |
| 2017 |
| Minnesota Twins |
| 14 |
| 8 |
| 26 |
| 145.2 |
| 3.89 |
| 1.23 |
| 139 |
| 48 |
| 15 |
| 8.59 |
| 2.97 |
| 2018 | Minnesota Twins | 12 | 11 | 32 | 192.1 | 3.84 | 1.14 | 202 | 61 | 25 | 9.45 | 2.85 |
| 2019 | Minnesota Twins | 14 | 8 | 32 | 200.1 | 3.68 | 1.22 | 195 | 51 | 26 | 8.76 | 2.29 |
| 2020 | Minnesota Twins | 5 | 4 | 12 | 63.0 | 4.00 | 1.32 | 68 | 26 | 8 | 9.71 | 3.71 |
| 2021 | Minnesota Twins | 7 | 5 | 20 | 121.2 | 3.48 | 1.04 | 126 | 32 | 14 | 9.32 | 2.37 |
| 2021 | Toronto Blue Jays | 5 | 4 | 12 | 70.1 | 3.58 | 1.09 | 78 | 13 | 8 | 9.98 | 1.66 |
| 2021 | 12 | 9 | 32 | 192.0 | 3.52 | 1.06 | 204 | 45 | 22 | 9.56 | 2.11 |
| 2022 | Toronto Blue Jays | 12 | 7 | 32 | 172.0 | 5.23 | 1.42 | 149 | 45 | 29 | 7.80 | 2.35 |
| 2023 | Toronto Blue Jays | 11 | 12 | 32 | 189.2 | 3.65 | 1.19 | 184 | 52 | 25 | 8.73 | 2.47 |
| 2024 | Toronto Blue Jays | 16 | 11 | 32 | 192.1 | 3.60 | 1.15 | 153 | 54 | 31 | 7.16 | 2.53 |
| 2025 | Toronto Blue Jays | 9 | 5 | 31 | 166.0 | 4.17 | 1.30 | 138 | 56 | 26 | 7.48 | 3.04 |
| Career | — | 108 | 82 | 275 | 1571.2 | 4.08 | 1.24 | 1,481 | 473 | 219 | 8.48 | 2.71 |
