| Year | Team | W | L | G | IP | ERA | WHIP | K | BB | HR | K/9 | BB/9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017 | New York Yankees | 9 | 7 | 29 | 155.1 | 3.88 | 1.23 | 144 | 51 | 21 | 8.34 | 2.95 |
| 2018 |
| New York Yankees |
| 2 |
| 0 |
| 6 |
| 27.1 |
| 3.62 |
| 1.35 |
| 23 |
| 12 |
| 3 |
| 7.57 |
| 3.95 |
| 2019 | New York Yankees | 0 | 0 | 2 | 4.0 | 6.75 | 1.75 | 5 | 0 | 1 | 11.25 | 0.00 |
| 2020 | New York Yankees | 2 | 3 | 10 | 44.0 | 5.11 | 1.30 | 47 | 9 | 7 | 9.61 | 1.84 |
| 2021 | New York Yankees | 6 | 7 | 30 | 157.1 | 3.83 | 1.28 | 162 | 51 | 19 | 9.27 | 2.92 |
| 2022 | New York Yankees | 3 | 3 | 21 | 114.2 | 3.69 | 1.10 | 97 | 23 | 15 | 7.61 | 1.81 |
| 2022 | St. Louis Cardinals | 6 | 3 | 11 | 63.2 | 3.11 | 1.08 | 61 | 13 | 6 | 8.62 | 1.84 |
| 2022 | 9 | 6 | 32 | 178.1 | 3.48 | 1.09 | 158 | 36 | 21 | 7.97 | 1.82 |
| 2023 | St. Louis Cardinals | 6 | 9 | 21 | 121.0 | 3.42 | 1.25 | 108 | 35 | 12 | 8.03 | 2.60 |
| 2023 | Texas Rangers | 4 | 2 | 11 | 67.2 | 2.79 | 1.09 | 58 | 13 | 6 | 7.71 | 1.73 |
| 2023 | 10 | 11 | 32 | 188.2 | 3.20 | 1.19 | 166 | 48 | 18 | 7.92 | 2.29 |
| 2024 | Arizona Diamondbacks | 8 | 7 | 25 | 117.0 | 6.23 | 1.65 | 83 | 44 | 14 | 6.38 | 3.38 |
| Career | — | 46 | 41 | 166 | 872.0 | 4.03 | 1.27 | 788 | 251 | 104 | 8.13 | 2.59 |
